Downtown St Louis Office Space for Rent

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Renting Office Space in Downtown St Louis

Downtown West has undergone a $820 million physical transformation, centered on the CityPark Stadium and the explosive growth of the City Foundry STL adaptive reuse project (Source: Lizzy Dooley RE 2025/2026). The neighborhood has successfully pivoted from a warehouse district into a high-density "Sports & Entertainment" hub, with the second phase of City Foundry (One Foundry Way) delivering luxury residential and retail in early 2026 (Source: Lawrence Group). 2026 is the year of "Geospatial Gravity." As the final move-ins for the NGA West campus begin just to the north, Downtown West is serving as the primary "off-campus" lifestyle hub for the 3,000+ intelligence employees. Expect continued demand for loft-style units and experiential retail as the neighborhood solidifies its status as the city's new "front door."

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Popular Office Space in the Downtown St Louis Neighborhood

S 4th Street

215 – 2,000 SF

$800 – $450,000 /mo

General

Deloitte Building

1,521 – 114,000 SF

$2,300 – $175,800 /mo

General

Duncan Ave

16,751 – 59,000 SF

$36,300 – $73,800 /mo

General

Locust St

750 – 29,191 SF

$900 – $34,100 /mo

Lafayette Ave Unit #E200

1,255 SF

$2,500 /mo

General

Great Office Space Across from the New MLS Stadium

1,629 – 8,553 SF

$2,200 – $11,400 /mo

Creative General

Incredible Standalone Office for Lease by MLS Stadium

2,500 SF

$4,000 /mo

General

Vande-East

15,000 – 16,600 SF

- /mo

General

2315 Pine Street For Lease

7,457 SF

$7,800 /mo

General

754 S 4th St

376 – 1,213 SF

$1,200 – $4,000 /mo

Creative General Storefront

Suite Rates in Downtown St Louis

Suite Sizes in Downtown St Louis

Neighborhood Comparison

Neighborhood	Average Available SQFT	Average Rate / SQFT PER Month	NUMBER OF AVAILABLE SUITES
Airport	2,300	$1.47 / SF	93
Chesterfield	1,800	$1.71 / SF	311
Downtown St Louis	2,600	$1.43 / SF	173
Fairview Heights	2,200	$0.81 / SF	52
Ferguson	9,700	$0.67 / SF	< 30
Midtown St Louis	2,600	$1.43 / SF	174
O'Fallon	4,600	$1.79 / SF	< 30
St Charles	2,400	$1.51 / SF	86

*All data is from sources we deem reliable and is tracked to provide tenants an understanding of market and submarket conditions, however we cannot guarantee accuracy and all data should be confirmed prior to any use in the lease or purchase of real property.