Sorrento Valley Commercial Office Space for Rent

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Renting Commercial Office Space in Sorrento Valley

Sorrento Valley is the "Biotech Engine" of San Diego. It is currently characterized by high density and high demand for specialized R&D facilities. While direct vacancy has inched up to 6.4%, leasing activity remains resilient, driven by small-to-mid-sized startups that prefer the "cluster effect" of being near established giants like Qualcomm (Source: NAI San Diego / Kidder Mathews). 2026 will be defined by "Sublease Digestion." Much of the current sublease inventory—concentrated in Sorrento Mesa—is expected to be absorbed by late 2026 as the funding environment for biotech firms stabilizes. Sorrento Valley remains a top choice for industrial and R&D investors due to its total lack of new developable land and its critical role in the regional tech supply chain (Source: Cushman & Wakefield Life Science Update).

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Popular Properties in the Sorrento Valley Neighborhood

Suite Rates in Sorrento Valley

Suite Sizes in Sorrento Valley

Neighborhood Comparison

Neighborhood Average Available SQFT Average Rate / SQFT PER Month NUMBER OF AVAILABLE SUITES
Carlsbad 1,900 $2.48 / SF 250
Carmel Valley 2,000 $3.08 / SF 391
Chula Vista 1,200 $1.47 / SF 63
Coronado - - < 30
Downtown 2,600 $3.05 / SF 500
El Cajon 1,400 $1.77 / SF 85
Esconsido 1,500 $1.39 / SF 99
Gaslamp District 2,600 $3.06 / SF 460
Grantville 1,600 $2.20 / SF 122
La Jolla 1,500 $3.20 / SF 213
La Mesa 1,500 $2.28 / SF 31
Little Italy 2,600 $3.07 / SF 445
Midway District 1,700 $8.33 / SF 44
Miramar 1,600 $2.41 / SF 92
Mission Valley 1,600 $2.48 / SF 214
National City 1,000 $28.96 / SF < 30
Oceanside 1,800 $2.06 / SF 518
Otay Mesa 34,000 $1.23 / SF < 30
Point Loma 1,200 $2.09 / SF 102
Rancho Bernardo 1,200 $2.65 / SF 89
Sorrento Valley 2,600 $2.07 / SF 126
Torrey Pines 2,100 $2.63 / SF 42
University Town Center 2,600 $3.21 / SF 238
*All data is from sources we deem reliable and is tracked to provide tenants an understanding of market and submarket conditions, however we cannot guarantee accuracy and all data should be confirmed prior to any use in the lease or purchase of real property.