2100 SIXTEENTH is prominently located in Birmingham’s Southside/Medical Center submarket, offering convenient access to UAB, St. Vincent’s Hospital, and Children’s of Alabama, with direct connectivity to the Red Mountain Expressway. The property is under new ownership and scheduled for exterior and common area renovations in Spring 2026. With strong surrounding institutional anchors, on‑site parking, and flexible layouts, the building is well positioned for medical and professional office tenants.